Enchilada sauce is easier to make than you think. Combine chopped tomatoes, onion, garlic with salt, cumin, red pepper flakes and chipotle pepper powder in a large saucepan, and bring to a boil. Cook until the tomatoes break down, then blend together and strain to create this sauce. Spicy Homemade Enchilada Sauce will a hit with anyone who loves heat with their enchiladas. This vegan sauce is perfect for topping enchiladas, as well as tacos, nachos and more!